JM91, a newly synthesized indoledione derivative, inhibits rat aortic vascular smooth muscle cells proliferation and cell cycle progression through inhibition of ERK1/2 and Akt activations.

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作者： Ji-Min,Seo ^[1] ; Yong-Ri,Jin ; Chung-Kyu,Ryu ; Tack-Joong,Kim ; Xiang-Hua,Han ; Jin-Tae,Hong ; Hwan-Soo,Yoo ; Chong-Kil,Lee ; Yeo-Pyo,Yun

作者单位： College of Pharmacy, CBITRC, Research Center for Bioresource and Health, Chungbuk National University, Cheongju 361-763, Republic of Korea. ^[1]

主题词动物(Animals);主动脉(Aorta);细胞周期(Cell Cycle);细胞周期蛋白质类(Cell Cycle Proteins);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);DNA(DNA);丝裂原活化蛋白激酶1(Mitogen-Activated Protein Kinase 1);丝裂原活化蛋白激酶3(Mitogen-Activated Protein Kinase 3);肌细胞, 平滑肌(Myocytes, Smooth Muscle);磷酰化(Phosphorylation);血小板源性生长因子(Platelet-Derived Growth Factor);蛋白激酶抑制剂(Protein Kinase Inhibitors);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);原癌基因蛋白质c-sis(Proto-Oncogene Proteins c-sis);喹诺酮类(Quinolones);醌类(Quinones);大鼠(Rats);视网膜母细胞瘤蛋白质(Retinoblastoma Protein)

DOI 10.1016/j.bcp.2007.11.013

PMID 18191105

发布时间 2019-12-10

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Biochemical pharmacology

2008年75卷6期

1331-40页

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JM91, a newly synthesized indoledione derivative, inhibits rat aortic vascular smooth muscle cells proliferation and cell cycle progression through inhibition of ERK1/2 and Akt activations.

Biochemical pharmacology

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Biochemical pharmacology

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JM91, a newly synthesized indoledione derivative, inhibits rat aortic vascular smooth muscle cells proliferation and cell cycle progression through inhibition of ERK1/2 and Akt activations.

Biochemical pharmacology

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Biochemical pharmacology

相关期刊

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