A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.
第一作者:
Yue,Zhao
第一单位:
Laboratory of Nuclear Signaling, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-0032, Japan.
作者:
主题词
氨基酸序列(Amino Acid Sequence);动物(Animals);动物, 基因修饰(Animals, Genetically Modified);细胞系(Cell Line);保守序列(Conserved Sequence);果蝇蛋白质类(Drosophila Proteins);黑腹果蝇(Drosophila melanogaster);内肽酶类(Endopeptidases);基因沉默(Gene Silencing);异染色质(Heterochromatin);组蛋白酰基转移酶(Histone Acetyltransferases);人类(Humans);分子序列数据(Molecular Sequence Data);多蛋白复合物(Multiprotein Complexes);启动区, 遗传(Promoter Regions, Genetic);蛋白质相互作用图谱(Protein Interaction Mapping);RNA聚合酶Ⅱ(RNA Polymerase II);受体, 雄激素(Receptors, Androgen);重组融合蛋白质类(Recombinant Fusion Proteins);序列比对(Sequence Alignment);序列同源性, 氨基酸(Sequence Homology, Amino Acid);硫酯水解酶类(Thiolester Hydrolases);反式激活因子类(Trans-Activators);转录因子(Transcription Factors);转录因子类, 普通(Transcription Factors, General);转录, 遗传(Transcription, Genetic);泛素硫酯酶(Ubiquitin Thiolesterase);泛素化(Ubiquitination);p300-CBP转录因子(p300-CBP Transcription Factors)
DOI
10.1016/j.molcel.2007.12.011
PMID
18206972
发布时间
2022-03-11
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Molecular cell
92-101页
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