HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
第一作者:
James,Arthos
第一单位:
Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA. jarthos@niaid.nih.gov
作者:
主题词
CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);细胞运动(Cell Movement);细胞, 培养的(Cells, Cultured);成纤维细胞(Fibroblasts);流式细胞术(Flow Cytometry);HIV包膜蛋白质gp120(HIV Envelope Protein gp120);HIV感染(HIV Infections);HIV-1(HIV-1);人类(Humans);整合素类(Integrins);肠黏膜(Intestinal Mucosa);杀伤细胞, 天然(Killer Cells, Natural);配体(Ligands);淋巴细胞功能相关抗原1(Lymphocyte Function-Associated Antigen-1);蛋白质结合(Protein Binding);信号传导(Signal Transduction)
DOI
10.1038/ni1566
PMID
18264102
发布时间
2022-03-18
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Nature immunology
301-9页
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