Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent.
第一作者:
D M,Appledorn
第一单位:
Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48823, USA
作者:
医学主题词
腺病毒科(Adenoviridae);动物(Animals);补体激活(Complement Activation);补体C4(Complement C4);细胞因子类(Cytokines);遗传载体(Genetic Vectors);人类(Humans);免疫, 先天(Immunity, Innate);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);血清分型(Serotyping);转导, 遗传(Transduction, Genetic);接种(Vaccination)
DOI
10.1038/gt.2008.18
PMID
18288208
发布时间
2012-11-15
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Gene therapy
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