Blebbistatin inhibits the chemotaxis of vascular smooth muscle cells by disrupting the myosin II-actin interaction.
第一作者:
Hong Hui,Wang
第一单位:
Department of Molecular and Cellular Pharmacology, Faculty of Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-Machi, Maebashi, Gunma, Japan.
作者:
医学主题词
肌动蛋白类(Actins);动物(Animals);牛(Cattle);细胞系(Cell Line);趋化作用(Chemotaxis);鸡(Chickens);剂量效应关系, 药物(Dose-Response Relationship, Drug);酶抑制剂(Enzyme Inhibitors);荧光共振能量转移(Fluorescence Resonance Energy Transfer);荧光抗体技术(Fluorescent Antibody Technique);豚鼠(Guinea Pigs);显微镜检查, 共焦(Microscopy, Confocal);显微镜检查, 电子(Microscopy, Electron);肌, 平滑, 血管(Muscle, Smooth, Vascular);肌细胞, 平滑肌(Myocytes, Smooth Muscle);肌球蛋白亚碎片(Myosin Subfragments);肌球蛋白Ⅱ型(Myosin Type II);磷酰化(Phosphorylation);磷酰胆碱(Phosphorylcholine);血小板源性生长因子(Platelet-Derived Growth Factor);蛋白质构象(Protein Conformation);原癌基因蛋白质c-sis(Proto-Oncogene Proteins c-sis);大鼠(Rats);鞘氨醇(Sphingosine)
DOI
10.1152/ajpheart.00970.2007
PMID
18296570
发布时间
2020-09-30
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