换一批Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells.
第一单位：
Division of Dermatologic Oncology, Department of Dermatology, University of Tuebingen, Tuebingen, Germany.
作者：
医学主题词
雄二烯类(Androstadienes);细胞凋亡(Apoptosis);苯磺酸盐类(Benzenesulfonates);丁二烯类(Butadienes);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);色酮类(Chromones);减量调节(Down-Regulation);类黄酮物质(Flavonoids);人类(Humans);黑色素瘤(Melanoma);丝裂原激活蛋白激酶激酶类(Mitogen-Activated Protein Kinase Kinases);吗啉类(Morpholines);多蛋白复合物(Multiprotein Complexes);肿瘤侵润(Neoplasm Invasiveness);烟酰胺(Niacinamide);腈类(Nitriles);苯脲化合物(Phenylurea Compounds);蛋白激酶抑制剂(Protein Kinase Inhibitors);蛋白质类(Proteins);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2);吡啶类(Pyridines);信号传导(Signal Transduction);西罗莫司(Sirolimus);皮肤肿瘤(Skin Neoplasms);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);转录因子(Transcription Factors)
DOI
10.1038/jid.2008.44
PMID
18323781
发布时间
2021-12-03
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