CXCL12/CXCR4 transactivates HER2 in lipid rafts of prostate cancer cells and promotes growth of metastatic deposits in bone.
第一作者:
Sreenivasa R,Chinni
第一单位:
Department of Urology, Wayne State University School of Medicine, Detroit, MI 48201, USA. schinni@med.wayne.edu
作者:
医学主题词
生物素化作用(Biotinylation);骨肿瘤(Bone Neoplasms);细胞分裂(Cell Division);细胞系, 肿瘤(Cell Line, Tumor);细胞膜(Cell Membrane);趋化因子CXCL12(Chemokine CXCL12);人类(Humans);男(雄)性(Male);膜微区(Membrane Microdomains);肿瘤侵润(Neoplasm Invasiveness);肿瘤转移(Neoplasm Metastasis);前列腺肿瘤(Prostatic Neoplasms);交叉感知受体(Receptor Cross-Talk);受体, CXCR4(Receptors, CXCR4);转录激活(Transcriptional Activation);转染(Transfection)
DOI
10.1158/1541-7786.MCR-07-0117
PMID
18337451
发布时间
2021-10-20
- 浏览7
Molecular cancer research
446-57页
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