Semaphorin 3B is a 1,25-Dihydroxyvitamin D3-induced gene in osteoblasts that promotes osteoclastogenesis and induces osteopenia in mice.
第一作者:
Amelia L M,Sutton
第一单位:
Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio 44106, USA.
作者:
医学主题词
动物(Animals);动物, 新生(Animals, Newborn);骨发育(Bone Development);骨疾病, 代谢性(Bone Diseases, Metabolic);骨和骨组织(Bone and Bones);COS细胞(COS Cells);骨化三醇(Calcitriol);细胞转分化(Cell Transdifferentiation);细胞, 培养的(Cells, Cultured);女(雌)性(Female);人类(Humans);男(雄)性(Male);膜糖蛋白类(Membrane Glycoproteins);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);成骨细胞(Osteoblasts);破骨细胞(Osteoclasts);信号素类(Semaphorins);增量调节(Up-Regulation)
DOI
10.1210/me.2007-0363
PMID
18356290
发布时间
2021-10-20
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