Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling.
第一作者:
Chang Hyun,Byon
第一单位:
Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
作者:
医学主题词
腺病毒科(Adenoviridae);动物(Animals);动脉粥样硬化(Atherosclerosis);钙质沉着症(Calcinosis);细胞, 培养的(Cells, Cultured);核心结合因子α1亚基(Core Binding Factor Alpha 1 Subunit);过氧化氢(Hydrogen Peroxide);小鼠(Mice);肌, 平滑, 血管(Muscle, Smooth, Vascular);氧化性应激(Oxidative Stress);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);信号传导(Signal Transduction);转录激活(Transcriptional Activation)
DOI
10.1074/jbc.M800021200
PMID
18378684
发布时间
2025-05-29
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