换一批
换一批BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells.
作者：
主题词
抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);凋亡调节蛋白质类(Apoptosis Regulatory Proteins);联苯化合物(Biphenyl Compounds);细胞系(Cell Line);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);DNA碎片裂(DNA Fragmentation);DNA, 肿瘤(DNA, Neoplasm);人类(Humans);肾(Kidney);膜蛋白质类(Membrane Proteins);硝基酚类(Nitrophenols);胰腺肿瘤(Pancreatic Neoplasms);哌嗪类(Piperazines);原癌基因蛋白质类(Proto-Oncogene Proteins);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2);磺胺类(Sulfonamides);TNF相关凋亡诱导配体(TNF-Related Apoptosis-Inducing Ligand);bcl-2同源拮抗杀伤蛋白质(bcl-2 Homologous Antagonist-Killer Protein)
DOI
10.1158/0008-5472.CAN-07-2508
PMID
18413764
发布时间
2022-03-31
- 浏览38
Cancer research
2944-51页
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