Peripheral T cells derived from Alzheimer's disease patients overexpress CXCR2 contributing to its transendothelial migration, which is microglial TNF-alpha-dependent.
第一作者:
Yi-Jun,Liu
第一单位:
Department of Developmental Biology, Key Laboratory of Cell Biology, Ministry of Public Health of China, China Medical University, Shenyang 110001, PR China.
作者:
医学主题词
老年人(Aged);老年人, 80以上(Aged, 80 and over);阿尔茨海默病(Alzheimer Disease);淀粉样β肽类(Amyloid beta-Peptides);动物(Animals);自身抗体(Autoantibodies);血脑屏障(Blood-Brain Barrier);脑(Brain);细胞运动(Cell Movement);内皮, 血管(Endothelium, Vascular);女(雌)性(Female);人类(Humans);白细胞介素8(Interleukin-8);男(雄)性(Male);小神经胶质细胞(Microglia);微血管(Microvessels);大鼠(Rats);大鼠, Wistar(Rats, Wistar);受体, 白细胞介素8B(Receptors, Interleukin-8B);T淋巴细胞(T-Lymphocytes);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)
DOI
10.1016/j.neurobiolaging.2008.03.024
PMID
18462836
发布时间
2020-12-22
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Neurobiology of aging
175-88页
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