换一批
换一批Chronic doxycycline exposure accelerates left ventricular hypertrophy and progression to heart failure in mice after thoracic aorta constriction.
作者：
主题词
动物(Animals);主动脉, 胸(Aorta, Thoracic);钙结合蛋白质类(Calcium-Binding Proteins);收缩(Constriction);疾病模型, 动物(Disease Models, Animal);疾病恶化(Disease Progression);多西环素(Doxycycline);纤维化(Fibrosis);心力衰竭(Heart Failure);血流动力学(Hemodynamics);肥大, 左心室(Hypertrophy, Left Ventricular);基质金属蛋白酶2(Matrix Metalloproteinase 2);基质金属蛋白酶9(Matrix Metalloproteinase 9);小鼠(Mice);心肌(Myocardium);肌球蛋白重链(Myosin Heavy Chains);利钠肽, 脑(Natriuretic Peptide, Brain);聚合酶链反应(Polymerase Chain Reaction);蛋白酶抑制药(Protease Inhibitors);兰尼碱受体钙释放通道(Ryanodine Receptor Calcium Release Channel);肌浆网钙转运ATP酶类(Sarcoplasmic Reticulum Calcium-Transporting ATPases);时间因素(Time Factors);超声检查(Ultrasonography);心室重构(Ventricular Remodeling)
DOI
10.1152/ajpheart.01101.2007
PMID
18487442
发布时间
2020-09-30
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