The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA.
作者:
主题词
肌动蛋白类(Actins);乳腺肿瘤(Breast Neoplasms);细胞系(Cell Line);细胞系, 肿瘤(Cell Line, Tumor);交联试剂(Cross-Linking Reagents);女(雌)性(Female);人类(Humans);基质金属蛋白酶14(Matrix Metalloproteinase 14);模型, 生物学(Models, Biological);突变蛋白质类(Mutant Proteins);肿瘤侵润(Neoplasm Invasiveness);蛋白质结合(Protein Binding);蛋白质加工, 转译后(Protein Processing, Post-Translational);蛋白质结构, 三级(Protein Structure, Tertiary);蛋白质亚单位(Protein Subunits);蛋白质转运(Protein Transport);伪足(Pseudopodia);膜泡运输蛋白质类(Vesicular Transport Proteins);cdc42 GTP结合蛋白质(cdc42 GTP-Binding Protein);ras GTP酶激活蛋白质类(ras GTPase-Activating Proteins);ρA GTP结合蛋白质(rhoA GTP-Binding Protein)
DOI
10.1083/jcb.200709076
PMID
18541705
发布时间
2021-10-20
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