换一批
换一批D77, one benzoic acid derivative, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75.
第一作者：
Li,Du
第一单位：
Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.
作者：
主题词
衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);动物(Animals);细菌蛋白质类(Bacterial Proteins);苯甲酸盐类(Benzoates);苯甲酸(Benzoic Acid);CHO细胞(CHO Cells);仓鼠亚科(Cricetinae);仓鼠属(Cricetulus);HIV整合酶(HIV Integrase);HIV整合酶抑制剂(HIV Integrase Inhibitors);HIV-1(HIV-1);人类(Humans);诱变(Mutagenesis);光感受器, 微生物(Photoreceptors, Microbial);噻唑烷二酮类(Thiazolidinediones);转录因子(Transcription Factors);双杂交系统技术(Two-Hybrid System Techniques);酵母菌(Yeasts)
DOI
10.1016/j.bbrc.2008.07.139
PMID
18691555
发布时间
2015-11-19
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