SCL/TAL1 interrupting locus derepresses GLI1 from the negative control of suppressor-of-fused in pancreatic cancer cell.
作者:
主题词
癌, 胰腺管(Carcinoma, Pancreatic Ductal);细胞核(Cell Nucleus);细胞, 培养的(Cells, Cultured);减量调节(Down-Regulation);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);猬蛋白质类(Hedgehog Proteins);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);模型, 生物学(Models, Biological);胰腺肿瘤(Pancreatic Neoplasms);蛋白质结合(Protein Binding);原癌基因蛋白质类(Proto-Oncogene Proteins);原癌基因蛋白质类p21(ras)(Proto-Oncogene Proteins p21(ras));阻遏蛋白质类(Repressor Proteins);转录因子(Transcription Factors);转染(Transfection);ras蛋白质类(ras Proteins)
DOI
10.1158/0008-5472.CAN-07-6661
PMID
18829525
发布时间
2016-11-24
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Cancer research
7723-9页
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