The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.
第一作者:
Efrat,Shema
第一单位:
Department of Molecular Cell Biology, The Weizmann Institute of Science, Rehovot 76100, Israel.
作者:
主题词
动物(Animals);乳腺肿瘤(Breast Neoplasms);细胞运动(Cell Movement);细胞转化, 肿瘤(Cell Transformation, Neoplastic);染色质(Chromatin);DNA甲基化(DNA Methylation);DNA, 肿瘤(DNA, Neoplasm);表皮生长因子(Epidermal Growth Factor);女(雌)性(Female);基因表达调控(Gene Expression Regulation);组蛋白类(Histones);人类(Humans);小鼠(Mice);小鼠, 裸(Mice, Nude);启动区, 遗传(Promoter Regions, Genetic);RNA聚合酶Ⅱ(RNA Polymerase II);RNA, 小分子干扰(RNA, Small Interfering);抑制, 遗传(Suppression, Genetic);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);肿瘤抑制蛋白质类(Tumor Suppressor Proteins);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);泛素化(Ubiquitination)
DOI
10.1101/gad.1703008
PMID
18832071
发布时间
2018-11-13
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Genes & development
2664-76页
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