IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans.
第一作者:
Isabelle,Isnardi
第一单位:
Laboratory of Biochemistry and Molecular Immunology, Hospital for Special Surgery, New York, NY 10021, USA.
作者:
医学主题词
抗体, 抗核(Antibodies, Antinuclear);自身抗体(Autoantibodies);自身免疫(Autoimmunity);B-淋巴细胞(B-Lymphocytes);儿童(Child);女(雌)性(Female);基因表达谱(Gene Expression Profiling);人类(Humans);婴儿(Infant);白细胞介素1受体相关激酶类(Interleukin-1 Receptor-Associated Kinases);淋巴细胞活化(Lymphocyte Activation);男(雄)性(Male);膜转运蛋白质类(Membrane Transport Proteins);髓样分化因子88(Myeloid Differentiation Factor 88);寡核苷酸序列分析(Oligonucleotide Array Sequence Analysis);重组蛋白质类(Recombinant Proteins);自身耐受性(Self Tolerance);Toll样受体(Toll-Like Receptors);青年人(Young Adult)
DOI
10.1016/j.immuni.2008.09.015
PMID
19006693
发布时间
2025-06-08
- 浏览8
Immunity
746-57页
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