A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk.
第一作者:
Nabila,Bouatia-Naji
第一单位:
CNRS-UMR-8090, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France.
作者:
医学主题词
衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);青少年(Adolescent);成年人(Adult);血糖(Blood Glucose);儿童(Child);染色体, 人, 11对(Chromosomes, Human, Pair 11);队列研究(Cohort Studies);糖尿病, 2型(Diabetes Mellitus, Type 2);禁食(Fasting);基因表达谱(Gene Expression Profiling);基因表达调控(Gene Expression Regulation);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);葡糖激酶(Glucokinase);人类(Humans);胰岛素抗药性(Insulin Resistance);胰岛(Islets of Langerhans);Meta分析(主题)(Meta-Analysis as Topic);中年人(Middle Aged);多态性, 单核苷酸(Polymorphism, Single Nucleotide);RNA, 信使(RNA, Messenger);受体, 褪黑激素, MT2(Receptor, Melatonin, MT2);受体, 褪黑激素(Receptors, Melatonin);结果可重复性(Reproducibility of Results)
DOI
10.1038/ng.277
PMID
19060909
发布时间
2025-05-29
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Nature genetics
89-94页
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