Inhibition of peroxisome proliferator-activated receptor gamma promotes tumorigenesis through activation of the beta-catenin / T cell factor (TCF) pathway in the mouse intestine.
第一作者:
Toshio,Fujisawa
第一单位:
Division of Gastroenterology, Yokohama City University School of Medicine, Japan.
作者:
主题词
动物(Animals);苯甲酰胺类(Benzamides);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);结肠(Colon);结肠肿瘤(Colonic Neoplasms);结肠息肉(Colonic Polyps);细胞周期蛋白D1(Cyclin D1);上皮(Epithelium);基因表达调控(Gene Expression Regulation);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);PPARγ(PPAR gamma);癌前状态(Precancerous Conditions);原癌基因蛋白质c-myc(Proto-Oncogene Proteins c-myc);吡啶类(Pyridines);TCF转录因子类(TCF Transcription Factors);β连环素(beta Catenin)
DOI
10.1254/jphs.08193fp
PMID
19075513
发布时间
2019-09-11
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