P2X receptors in sensory neurons co-cultured with cancer cells exhibit a decrease in opioid sensitivity.
第一作者:
I,Chizhmakov
第一单位:
Bogomoletz Institute of Physiology, Ukraine Bogomoletz Institute of Physiology, Kiev, Ukraine.
作者:
主题词
腺苷三磷酸(Adenosine Triphosphate);镇痛药, 阿片类(Analgesics, Opioid);动物(Animals);细胞培养技术(Cell Culture Techniques);细胞系, 肿瘤(Cell Line, Tumor);细胞, 培养的(Cells, Cultured);共同培养技术(Coculture Techniques);减量调节(Down-Regulation);抗药性(Drug Resistance);纤维肉瘤(Fibrosarcoma);动力学(Kinetics);膜电位(Membrane Potentials);肿瘤(Neoplasms);疼痛感受器(Nociceptors);结状神经节(Nodose Ganglion);寡肽类(Oligopeptides);膜片钳术(Patch-Clamp Techniques);大鼠(Rats);大鼠, Wistar(Rats, Wistar);受体, 阿片样, μ(Receptors, Opioid, mu);受体, 嘌呤能P2(Receptors, Purinergic P2);受体, 嘌呤能P2X(Receptors, Purinergic P2X);感觉感受器细胞(Sensory Receptor Cells);时间因素(Time Factors)
DOI
10.1111/j.1460-9568.2008.06556.x
PMID
19077126
发布时间
2021-10-20
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