A 6-thioguanine nucleotide threshold level of 400 pmol/8 x 10(8) erythrocytes predicts azathioprine refractoriness in patients with inflammatory bowel disease and normal TPMT activity.
作者:
主题词
成年人(Adult);硫唑嘌呤(Azathioprine);抗药性(Drug Resistance);红细胞(Erythrocytes);女(雌)性(Female);鸟嘌呤核苷酸类(Guanine Nucleotides);人类(Humans);免疫抑制剂(Immunosuppressive Agents);炎性肠疾病(Inflammatory Bowel Diseases);男(雄)性(Male);甲基转移酶类(Methyltransferases);中年人(Middle Aged);前瞻性研究(Prospective Studies);硫鸟嘌呤(Thioguanine);硫代核苷酸类(Thionucleotides);治疗结果(Treatment Outcome)
DOI
10.1111/j.1572-0241.2008.01743.x
PMID
19086961
发布时间
2013-11-21
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