Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis.
第一作者:
Kevin K,Kim
第一单位:
Pulmonary and Critical Care Division, Department of Medicine, and Cardiovascular Research Institute, UCSF, San Francisco, CA 94143, USA.
作者:
主题词
急性肺损伤(Acute Lung Injury);动物(Animals);抗生素类, 抗肿瘤(Antibiotics, Antineoplastic);博来霉素(Bleomycin);细胞, 培养的(Cells, Cultured);上皮细胞(Epithelial Cells);成纤维细胞(Fibroblasts);人类(Humans);整合素α3β1(Integrin alpha3beta1);肺(Lung);中胚层(Mesoderm);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);表型(Phenotype);肺纤维化(Pulmonary Fibrosis);信号传导(Signal Transduction);Smad2蛋白质(Smad2 Protein);β连环素(beta Catenin)
DOI
10.1172/JCI36940
PMID
19104148
发布时间
2022-03-09
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