Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors.
作者:
主题词
衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);动物(Animals);碱性螺旋-环-螺旋转录因子类(Basic Helix-Loop-Helix Transcription Factors);细胞系(Cell Line);染色质免疫沉淀法(Chromatin Immunoprecipitation);DNA结合蛋白质类(DNA-Binding Proteins);胚胎, 哺乳动物(Embryo, Mammalian);GATA转录因子类(GATA Transcription Factors);基因表达调控, 发育期(Gene Expression Regulation, Developmental);基因组(Genome);白血病(Leukemia);金属蛋白质类(Metalloproteins);小鼠(Mice);蛋白质结合(Protein Binding);原癌基因蛋白质类(Proto-Oncogene Proteins);末端转移酶端粒(Telomerase);组织阵列分析(Tissue Array Analysis);反式激活因子类(Trans-Activators)
DOI
10.1182/blood-2008-11-187757
PMID
19171877
发布时间
2021-10-20
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Blood
5783-92页
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