首页> Journal of medicinal chemistry> Discovery of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a selective and orally efficacious inhibitor of the Met kinase superfamily.

Discovery of N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a selective and orally efficacious inhibitor of the Met kinase superfamily.

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第一作者： Gretchen M,Schroeder

第一单位： Bristol-Myers Squibb Research and Development, Princeton, New Jersey, 08543-4000, USA. gretchen.schroeder@bms.com

作者： Gretchen M,Schroeder ^[1] ; Yongmi,An ; Zhen-Wei,Cai ; Xiao-Tao,Chen ; Cheryl,Clark ; Lyndon A M,Cornelius ; Jun,Dai ; Johnni,Gullo-Brown ; Ashok,Gupta ; Benjamin,Henley ; John T,Hunt ; Robert,Jeyaseelan ; Amrita,Kamath ; Kyoung,Kim ; Jonathan,Lippy ; Louis J,Lombardo ; Veeraswamy,Manne ; Simone,Oppenheimer ; John S,Sack ; Robert J,Schmidt ; Guoxiang,Shen ; Kevin,Stefanski ; John S,Tokarski ; George L,Trainor ; Barri S,Wautlet ; Donna,Wei ; David K,Williams ; Yingru,Zhang ; Yueping,Zhang ; Joseph,Fargnoli ; Robert M,Borzilleri

作者单位： Bristol-Myers Squibb Research and Development, Princeton, New Jersey, 08543-4000, USA. gretchen.schroeder@bms.com ^[1]