Matrix metalloproteinase-2-deficient fibroblasts exhibit an alteration in the fibrotic response to connective tissue growth factor/CCN2 because of an increase in the levels of endogenous fibronectin.
第一作者:
Cristian A,Droppelmann
第一单位:
Centro de Regulación Celular y Patología, Centro de Regeneración y Envejecimiento, Departamento de Biología Celular y Molecular, Millenium Institute for Fundamental and Applied Biology, Pontificia Universidad Católica de Chile, Casilla 114-D, Santiago, Chile.
作者:
主题词
动物(Animals);结缔组织生长因子(Connective Tissue Growth Factor);二肽类(Dipeptides);细胞外基质(Extracellular Matrix);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);成纤维细胞(Fibroblasts);纤连蛋白类(Fibronectins);基因表达调控, 酶学(Gene Expression Regulation, Enzymologic);整合素αV(Integrin alphaV);基质金属蛋白酶2(Matrix Metalloproteinase 2);小鼠(Mice);NIH 3T3细胞(NIH 3T3 Cells);磷酰化(Phosphorylation);蛋白酶抑制药(Protease Inhibitors);RNA, 信使(RNA, Messenger);张力纤维(Stress Fibers)
DOI
10.1074/jbc.M807352200
PMID
19276073
发布时间
2021-10-20
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The Journal of biological chemistry
13551-13561页
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