Endogenous expression of Hras(G12V) induces developmental defects and neoplasms with copy number imbalances of the oncogene.
第一作者:
Xu,Chen
第一单位:
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
作者:
主题词
等位基因(Alleles);动物(Animals);DNA突变分析(DNA Mutational Analysis);基因表达调控, 发育期(Gene Expression Regulation, Developmental);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);疾病遗传易感性(Genetic Predisposition to Disease);免疫组织化学(Immunohistochemistry);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);突变(Mutation);肿瘤(Neoplasms);癌基因(Oncogenes);信号传导(Signal Transduction);体层摄影术, X线计算机(Tomography, X-Ray Computed);ras蛋白质类(ras Proteins)
DOI
10.1073/pnas.0900343106
PMID
19416908
发布时间
2022-03-09
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