The (+)- and (-)-gossypols potently inhibit both 3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase 3 in human and rat testes.
第一作者:
Guo-Xin,Hu
第一单位:
Institute of Molecular Toxicology & Pharmacology, Wenzhou Medical College, Zhejiang, PR China.
作者:
主题词
17-羟甾类脱氢酶类(17-Hydroxysteroid Dehydrogenases);动物(Animals);抗肿瘤药(Antineoplastic Agents);结合, 竞争性(Binding, Competitive);棉酚(Gossypol);人类(Humans);半数抑制浓度(Inhibitory Concentration 50);男(雄)性(Male);大鼠(Rats);种特异性(Species Specificity);睾丸(Testis)
DOI
10.1016/j.jsbmb.2009.02.004
PMID
19429456
发布时间
2013-11-21
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