Rationale and design of a trial evaluating the effects of losartan vs. nebivolol vs. the association of both on the progression of aortic root dilation in Marfan syndrome with FBN1 gene mutations.
作者:
主题词
青少年(Adolescent);肾上腺素能β受体拮抗剂(Adrenergic beta-Antagonists);成年人(Adult);血管紧张素Ⅱ1型受体拮抗剂(Angiotensin II Type 1 Receptor Blockers);主动脉瘤(Aortic Aneurysm);苯吡喃类(Benzopyrans);儿童(Child);儿童, 学龄前(Child, Preschool);扩张, 病理性(Dilatation, Pathologic);疾病恶化(Disease Progression);乙醇胺类(Ethanolamines);女(雌)性(Female);人类(Humans);婴儿(Infant);洛沙坦(Losartan);男(雄)性(Male);马凡综合征(Marfan Syndrome);微丝蛋白质类(Microfilament Proteins);中年人(Middle Aged);突变(Mutation);生活质量(Quality of Life);研究设计(Research Design);时间因素(Time Factors);转化生长因子β(Transforming Growth Factor beta);治疗结果(Treatment Outcome);青年人(Young Adult)
DOI
10.2459/JCM.0b013e3283232a45
PMID
19430350
发布时间
2021-10-28
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