The novel CXCR4 antagonist KRH-3955 is an orally bioavailable and extremely potent inhibitor of human immunodeficiency virus type 1 infection: comparative studies with AMD3100.

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作者： Tsutomu,Murakami ^[1] ; Sei,Kumakura ; Toru,Yamazaki ; Reiko,Tanaka ; Makiko,Hamatake ; Kazu,Okuma ; Wei,Huang ; Jonathan,Toma ; Jun,Komano ; Mikiro,Yanaka ; Yuetsu,Tanaka ; Naoki,Yamamoto

作者单位： AIDS Research Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, Japan. ^[1]

主题词动物(Animals);抗HIV药(Anti-HIV Agents);CHO细胞(CHO Cells);钙信号(Calcium Signaling);细胞系(Cell Line);细胞, 培养的(Cells, Cultured);趋化因子CXCL12(Chemokine CXCL12);仓鼠亚科(Cricetinae);仓鼠属(Cricetulus);荧光抗体技术(Fluorescent Antibody Technique);HIV感染(HIV Infections);HIV-1(HIV-1);人类(Humans);小鼠(Mice);小鼠, SCID(Mice, SCID);蛋白质结合(Protein Binding);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);受体, CXCR4(Receptors, CXCR4)

DOI 10.1128/AAC.01727-08

PMID 19451305

发布时间 2021-10-20

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Antimicrobial agents and chemotherapy

2009年53卷7期

2940-8页

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The novel CXCR4 antagonist KRH-3955 is an orally bioavailable and extremely potent inhibitor of human immunodeficiency virus type 1 infection: comparative studies with AMD3100.

Antimicrobial agents and chemotherapy

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Antimicrobial agents and chemotherapy

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The novel CXCR4 antagonist KRH-3955 is an orally bioavailable and extremely potent inhibitor of human immunodeficiency virus type 1 infection: comparative studies with AMD3100.

Antimicrobial agents and chemotherapy

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Antimicrobial agents and chemotherapy

相关期刊

检索历史清除