Negative regulation of Stat3 by activating PTPN11 mutants contributes to the pathogenesis of Noonan syndrome and juvenile myelomonocytic leukemia.

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第一作者： Wenjun,Zhang

第一单位： Herman B. Wells Center for Pediatric Research, Indianapolis, Indiana 46202; Riley Heart Research Center, Indianapolis, Indiana 46202; the Departments of Microbiology and Immunology, Indianapolis, Indiana 46202.

作者： Wenjun,Zhang ^[1] ; Rebecca J,Chan ^[2] ; Hanying,Chen ^[3] ; Zhenyun,Yang ^[4] ; Yantao,He ^[5] ; Xian,Zhang ^[5] ; Yong,Luo ^[5] ; Fuqing,Yin ^[4] ; Akira,Moh ^[6] ; Lucy C,Miller ^[4] ; R Mark,Payne ^[7] ; Zhong-Yin,Zhang ^[5] ; Xin-Yuan,Fu ^[6] ; Weinian,Shou ^[8]

作者单位： Herman B. Wells Center for Pediatric Research, Indianapolis, Indiana 46202; Riley Heart Research Center, Indianapolis, Indiana 46202; the Departments of Microbiology and Immunology, Indianapolis, Indiana 46202. ^[1] Herman B. Wells Center for Pediatric Research, Indianapolis, Indiana 46202; Section of Neonatology, Department of Pediatrics, Indianapolis, Indiana 46202. ^[2] Herman B. Wells Center for Pediatric Research, Indianapolis, Indiana 46202. ^[3] Section of Neonatology, Department of Pediatrics, Indianapolis, Indiana 46202. ^[4] Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana 46202. ^[5] the Departments of Microbiology and Immunology, Indianapolis, Indiana 46202. ^[6] Herman B. Wells Center for Pediatric Research, Indianapolis, Indiana 46202; Riley Heart Research Center, Indianapolis, Indiana 46202. ^[7] Herman B. Wells Center for Pediatric Research, Indianapolis, Indiana 46202; Riley Heart Research Center, Indianapolis, Indiana 46202; Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana 46202. ^[8]