The role of IGF-1 receptor and insulin receptor signaling for the pathogenesis of Alzheimer's disease: from model organisms to human disease.
第一作者:
S,Freude
第一单位:
Department of Internal Medicine II, Center for Molecular Medicine Cologne (CMMC), and Cologne Excellence Cluster on Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Köln, Kerpener Str. 62, 50937 Köln, Germany.
作者:
医学主题词
阿尔茨海默病(Alzheimer Disease);淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);淀粉样β肽类(Amyloid beta-Peptides);动物(Animals);疾病模型, 动物(Disease Models, Animal);人类(Humans);模型, 生物学(Models, Biological);受体, IGF1型(Receptor, IGF Type 1);受体, 胰岛素(Receptor, Insulin);信号传导(Signal Transduction);tau蛋白质类(tau Proteins)
DOI
10.2174/156720509788486527
PMID
19519303
发布时间
2019-10-27
- 浏览87
Current Alzheimer research
213-23页
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