Disruption of the OCH1 and MNN1 genes decrease N-glycosylation on glycoprotein expressed in Kluyveromyces lactis.
第一作者:
Bo,Liu
第一单位:
Department of Microorganism Engineering, Beijing Institute of Biotechnology, 20 Dongdajie Street, Fengtai District, Beijing 100071, China.
作者:
医学主题词
电泳(Electrophoresis);真菌蛋白质类(Fungal Proteins);基因缺失(Gene Deletion);基因敲除技术(Gene Knockout Techniques);基因, 报告(Genes, Reporter);糖基化(Glycosylation);粒细胞巨噬细胞集落刺激因子(Granulocyte-Macrophage Colony-Stimulating Factor);人类(Humans);克鲁维酵母属(Kluyveromyces);甘露糖基转移酶类(Mannosyltransferases);膜糖蛋白类(Membrane Glycoproteins);寡糖类(Oligosaccharides);多糖类(Polysaccharides);蛋白质工程(Protein Engineering);重组融合蛋白质类(Recombinant Fusion Proteins);血清白蛋白(Serum Albumin)
DOI
10.1016/j.jbiotec.2009.06.016
PMID
19559061
发布时间
2009-08-17
- 浏览26
Journal of biotechnology
95-102页
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