换一批Simvastatin attenuates microglial cells and astrocyte activation and decreases interleukin-1beta level after traumatic brain injury.
第一作者：
Bo,Li
第一单位：
Department of Neurosurgery, Henry Ford Health System, Detroit, Michigan, USA.
作者：
医学主题词
方差分析(Analysis of Variance);动物(Animals);抗原, CD(Antigens, CD);抗原, 分化, 髓单核细胞(Antigens, Differentiation, Myelomonocytic);星形细胞(Astrocytes);脑损伤(Brain Injuries);疾病模型, 动物(Disease Models, Animal);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);基因表达调控(Gene Expression Regulation);神经胶质原纤维酸性蛋白质(Glial Fibrillary Acidic Protein);羟甲基戊二酰基CoA还原酶抑制剂(Hydroxymethylglutaryl-CoA Reductase Inhibitors);白细胞介素1β(Interleukin-1beta);男(雄)性(Male);小神经胶质细胞(Microglia);大鼠(Rats);大鼠, Wistar(Rats, Wistar);斯伐他汀(Simvastatin);时间因素(Time Factors)
DOI
10.1227/01.NEU.0000346272.76537.DC
PMID
19574840
发布时间
2025-05-29
基金项目
R01 NS052280/NS/NINDS NIH HHS/United States
R01NS052280-01A1/NS/NINDS NIH HHS/United States
- 浏览139
Neurosurgery
179-85; discussion 185-6页
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