换一批Influence of the stereoisomeric position of the reactive acetate groups of the benzo[b]acronycine derivative S23906-1 on its DNA alkylation, helix-opening, cytotoxic, and antitumor activities.
第一作者：
Sabine,Depauw
第一单位：
INSERM-U837, Centre de Recherches Jean-Pierre Aubert (JPARC), Team-4 "Molecular and Cellular Targeting for Cancer Treatment," Institut pour la Recherche sur le Cancer de Lille, Place de Verdun, F-59045 Lille, France.
作者：
医学主题词
阿克罗宁(Acronine);动物(Animals);抗肿瘤药, 烷基化(Antineoplastic Agents, Alkylating);催化域(Catalytic Domain);细胞分裂(Cell Division);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);细胞毒素类(Cytotoxins);DNA加合物(DNA Adducts);人类(Humans);嵌入剂(Intercalating Agents);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 近交DBA(Mice, Inbred DBA);肿瘤, 实验性(Neoplasms, Experimental);立体异构现象(Stereoisomerism)
DOI
10.1124/mol.109.057554
PMID
19752199
发布时间
2025-02-13
- 浏览28
Molecular pharmacology
1172-85页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
