Identification of a region in the human IRS2 promoter essential for stress induced transcription depending on SP1, NFI binding and ERK activation in HepG2 cells.
第一作者:
M,Udelhoven
第一单位:
Department of Internal Medicine II, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Kerpener Strasse 62, 50937 Cologne, Germany.
作者:
医学主题词
酶激活(Enzyme Activation);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);基因表达调控(Gene Expression Regulation);葡萄糖(Glucose);Hep G2细胞(Hep G2 Cells);人类(Humans);胰岛素受体底物蛋白质类(Insulin Receptor Substrate Proteins);白细胞介素1β(Interleukin-1beta);模型, 遗传学(Models, Genetic);NFI转录因子类(NFI Transcription Factors);器官特异性(Organ Specificity);氧化性应激(Oxidative Stress);PPARγ(PPAR gamma);启动区, 遗传(Promoter Regions, Genetic);蛋白质结合(Protein Binding);蛋白激酶抑制剂(Protein Kinase Inhibitors);Sp1转录因子(Sp1 Transcription Factor);应激, 生理学(Stress, Physiological);转录, 遗传(Transcription, Genetic)
DOI
10.1677/JME-08-0182
PMID
19755487
发布时间
2013-11-21
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