Blockade of ethanol-induced potentiation of glycine receptors by a peptide that interferes with Gbetagamma binding.
第一作者:
Leonardo,Guzman
第一单位:
Laboratory of Neurophysiology, Department of Physiology, University of Concepción, Concepción, Chile.
作者:
医学主题词
氨基酸序列(Amino Acid Sequence);结合部位(Binding Sites);细胞系(Cell Line);电生理学(Electrophysiology);大肠杆菌(Escherichia coli);乙醇(Ethanol);G蛋白偶联内向整流钾通道(G Protein-Coupled Inwardly-Rectifying Potassium Channels);GTP结合蛋白质β亚单位(GTP-Binding Protein beta Subunits);GTP结合蛋白质γ亚单位(GTP-Binding Protein gamma Subunits);谷胱甘肽转移酶(Glutathione Transferase);人类(Humans);模型, 分子(Models, Molecular);分子序列数据(Molecular Sequence Data);肽碎片(Peptide Fragments);蛋白质结合(Protein Binding);蛋白质构象(Protein Conformation);蛋白质亚单位(Protein Subunits);受体, GABA-B(Receptors, GABA-B);受体, 甘氨酸(Receptors, Glycine);重组融合蛋白质类(Recombinant Fusion Proteins);信号传导(Signal Transduction)
DOI
10.1124/jpet.109.160440
PMID
19773530
发布时间
2025-03-06
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