换一批Overproduction of phosphoprotein enriched in diabetes (PED) induces mesangial expansion and upregulates protein kinase C-beta activity and TGF-beta1 expression.
第一作者：
F,Oriente
第一单位：
Department of Cellular and Molecular Biology and Pathology, Federico II University of Naples, Via Pansini 5, 80131, Naples, Italy.
作者：
医学主题词
肌动蛋白类(Actins);动物(Animals);星形细胞(Astrocytes);血压(Blood Pressure);DNA引物(DNA Primers);糖尿病, 1型(Diabetes Mellitus, Type 1);糖尿病, 2型(Diabetes Mellitus, Type 2);糖尿病肾病(Diabetic Nephropathies);脂肪酸类, 非酯化(Fatty Acids, Nonesterified);纤连蛋白类(Fibronectins);基因表达调控(Gene Expression Regulation);心率(Heart Rate);人类(Humans);胰岛素(Insulin);肾(Kidney);肾功能衰竭, 慢性(Kidney Failure, Chronic);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);小鼠, 转基因(Mice, Transgenic);表型(Phenotype);磷蛋白类(Phosphoproteins);蛋白激酶C(Protein Kinase C);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);Smad2蛋白质(Smad2 Protein);转化生长因子β1(Transforming Growth Factor beta1);增量调节(Up-Regulation)
DOI
10.1007/s00125-009-1528-z
PMID
19789852
发布时间
2025-05-29
- 浏览18
Diabetologia
2642-52页
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