PU.1 activation relieves GATA-1-mediated repression of Cebpa and Cbfb during leukemia differentiation.
作者:
主题词
CCAAT增强子结合蛋白类(CCAAT-Enhancer-Binding Proteins);细胞分化(Cell Differentiation);细胞转化, 肿瘤(Cell Transformation, Neoplastic);核心结合因子β亚基(Core Binding Factor beta Subunit);GATA1转录因子(GATA1 Transcription Factor);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);组蛋白类(Histones);人类(Humans);白血病(Leukemia);髓系细胞(Myeloid Cells);原癌基因蛋白质类(Proto-Oncogene Proteins);RNA干扰(RNA Interference);RNA, 小分子干扰(RNA, Small Interfering);重组融合蛋白质类(Recombinant Fusion Proteins);调节元件, 转录(Regulatory Elements, Transcriptional);阻遏蛋白质类(Repressor Proteins);反式激活因子类(Trans-Activators);转录激活(Transcriptional Activation)
DOI
10.1158/1541-7786.MCR-09-0031
PMID
19825991
发布时间
2024-06-08
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Molecular cancer research
1693-703页
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