换一批
换一批High anti tumor activity against rhabdomyosarcoma cells and low normal cells cytotoxicity of heat shock protein 90 inhibitors, with special emphasis on 17-[2-(pyrrolidin-1-yl)ethyl]-aminno-17-demethoxygeldanamycin.
第一作者：
E,Lukasiewicz
第一单位：
Department of Transplantation, Polish-American Institute of Pediatrics, Jagiellonian University School of Medicine, Cracow, Poland.
作者：
主题词
抗生素类, 抗肿瘤(Antibiotics, Antineoplastic);细胞凋亡(Apoptosis);苯醌类(Benzoquinones);印迹法, 蛋白质(Blotting, Western);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);趋化作用(Chemotaxis);上皮细胞(Epithelial Cells);HSP90热休克蛋白质类(HSP90 Heat-Shock Proteins);人类(Humans);内酰胺类, 大环(Lactams, Macrocyclic);基质金属蛋白酶2(Matrix Metalloproteinase 2);间质干细胞(Mesenchymal Stem Cells);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);横纹肌肉瘤(Rhabdomyosarcoma)
PMID
19826195
发布时间
2018-12-01
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