换一批Functional expression of an arachnid sodium channel reveals residues responsible for tetrodotoxin resistance in invertebrate sodium channels.
第一作者：
Yuzhe,Du
第一单位：
Department of Entomology, Genetics and Neuroscience Programs, Michigan State University, East Lansing, Michigan 48824, USA.
作者：
医学主题词
氨基酸序列(Amino Acid Sequence);动物(Animals);DNA, 互补(DNA, Complementary);剂量效应关系, 药物(Dose-Response Relationship, Drug);基因表达调控(Gene Expression Regulation);半数抑制浓度(Inhibitory Concentration 50);模型, 生物学(Models, Biological);分子序列数据(Molecular Sequence Data);诱变, 定点(Mutagenesis, Site-Directed);卵母细胞(Oocytes);序列同源性, 氨基酸(Sequence Homology, Amino Acid);钠通道(Sodium Channels);河豚毒素(Tetrodotoxin);瓦螨科(Varroidae);爪蟾属(Xenopus)
DOI
10.1074/jbc.M109.045690
PMID
19828457
发布时间
2021-10-20
基金项目
R01 GM057440/GM/NIGMS NIH HHS/United States
GM057440/GM/NIGMS NIH HHS/United States
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