Regulated cleavage of prothrombin by prothrombinase: repositioning a cleavage site reveals the unique kinetic behavior of the action of prothrombinase on its compound substrate.
第一作者:
Harlan N,Bradford
第一单位:
Joseph Stokes Research Institute, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
作者:
医学主题词
氨基酸序列(Amino Acid Sequence);动物(Animals);精氨酸(Arginine);催化域(Catalytic Domain);细胞系(Cell Line);人类(Humans);动力学(Kinetics);模型, 分子(Models, Molecular);分子序列数据(Molecular Sequence Data);突变蛋白质类(Mutant Proteins);凝血酶原(Prothrombin);底物特异性(Substrate Specificity);野猪(Sus scrofa);凝血致活酶(Thromboplastin)
DOI
10.1074/jbc.M109.070334
PMID
19858193
发布时间
2021-10-20
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