Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis.
第一作者:
Jingxian,Yang
第一单位:
Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
作者:
医学主题词
成体干细胞(Adult Stem Cells);动物(Animals);细胞凋亡(Apoptosis);细胞分化(Cell Differentiation);脑脊髓炎, 自身免疫性, 实验性(Encephalomyelitis, Autoimmune, Experimental);Fas配体蛋白质(Fas Ligand Protein);女(雌)性(Female);遗传工程(Genetic Engineering);绿色荧光蛋白质类(Green Fluorescent Proteins);免疫调节(Immunomodulation);白细胞介素10(Interleukin-10);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);多能干细胞(Multipotent Stem Cells);神经纤维, 有髓鞘的(Nerve Fibers, Myelinated);神经元(Neurons);重组蛋白质类(Recombinant Proteins);T淋巴细胞(T-Lymphocytes);时间因素(Time Factors);转导, 遗传(Transduction, Genetic)
DOI
10.1172/JCI37914
PMID
19884657
发布时间
2026-01-13
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