Identification of potent chemotypes targeting Leishmania major using a high-throughput, low-stringency, computationally enhanced, small molecule screen.
第一作者:
Elizabeth R,Sharlow
第一单位:
University of Pittsburgh Drug Discovery Institute and the Pittsburgh Molecular Library Screening Center, Pittsburgh, Pennsylvania, USA.
作者:
主题词
抗原虫药(Antiprotozoal Agents);细胞系(Cell Line);计算生物学(Computational Biology);药物评价, 临床前(Drug Evaluation, Preclinical);高通量筛选分析(High-Throughput Screening Assays);人类(Humans);硕大利什曼原虫(Leishmania major);利什曼病, 皮肤(Leishmaniasis, Cutaneous);寄生虫敏感性试验(Parasitic Sensitivity Tests);小分子化合物库(Small Molecule Libraries)
DOI
10.1371/journal.pntd.0000540
PMID
19888337
发布时间
2021-10-20
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