CCR7 deficiency exacerbates injury in acute nephritis due to aberrant localization of regulatory T cells.
第一作者:
Kathrin,Eller
第一单位:
Innsbruck Medical University, Clinical Division of Internal Medicine IV-Nephrology and Hypertension, Anichstrasse. 35, 6020 Innsbruck, Austria.
作者:
医学主题词
急性病(Acute Disease);动物(Animals);细胞运动(Cell Movement);细胞因子类(Cytokines);疾病模型, 动物(Disease Models, Animal);减量调节(Down-Regulation);免疫系统(Immune System);肾(Kidney);淋巴结(Lymph Nodes);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 基因敲除(Mice, Knockout);肾炎(Nephritis);受体, CCR7(Receptors, CCR7);疾病严重程度指数(Severity of Illness Index);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory)
DOI
10.1681/ASN.2009020133
PMID
19917782
发布时间
2021-10-20
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