Anti-tumor activity and mechanisms of a novel vascular disrupting agent, (Z)-3,4',5-trimethoxylstilbene-3'-O-phosphate disodium (M410).
第一作者:
Yu-Chen,Cai
第一单位:
State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, China.
作者:
主题词
血管生成抑制剂(Angiogenesis Inhibitors);动物(Animals);抗肿瘤药(Antineoplastic Agents);牛(Cattle);细胞周期(Cell Cycle);细胞死亡(Cell Death);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);结肠肿瘤(Colonic Neoplasms);减量调节(Down-Regulation);内皮细胞(Endothelial Cells);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);缺氧诱导因子1, α亚基(Hypoxia-Inducible Factor 1, alpha Subunit);半数抑制浓度(Inhibitory Concentration 50);肝(Liver);男(雄)性(Male);小鼠(Mice);聚合(Polymerization);二苯乙烯类(Stilbenes);微管蛋白(Tubulin);脐静脉(Umbilical Veins);血管内皮生长因子A(Vascular Endothelial Growth Factor A);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1007/s10637-009-9366-x
PMID
20012336
发布时间
2021-10-20
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Investigational new drugs
300-11页
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