Mice with a selective impairment of IFN-gamma signaling in macrophage lineage cells demonstrate the critical role of IFN-gamma-activated macrophages for the control of protozoan parasitic infections in vivo.
第一作者:
Jennifer E,Lykens
第一单位:
Division of Immunobiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.
作者:
医学主题词
动物(Animals);细胞谱系(Cell Lineage);干扰素γ(Interferon-gamma);硕大利什曼原虫(Leishmania major);巨噬细胞(Macrophages);小鼠(Mice);小鼠, 突变型(Mice, Mutant Strains);原虫感染(Protozoan Infections);受体, 干扰素(Receptors, Interferon);信号传导(Signal Transduction);弓形虫属(Toxoplasma);克鲁斯锥虫(Trypanosoma cruzi)
DOI
10.4049/jimmunol.0902346
PMID
20018611
发布时间
2025-05-29
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