换一批Evaluation of a dual-wavelength size exclusion HPLC method with improved sensitivity to detect protein aggregates and its use to better characterize degradation pathways of an IgG1 monoclonal antibody.
第一作者：
Michael D,Bond
第一单位：
BioPharmaceutical Development and Marketed Product Support, Centocor R&D, Inc., 145 King of Prussia Road, Radnor, Pennsylvania 19087, USA. mbond@its.jnj.com
作者：
医学主题词
抗体, 单克隆(Antibodies, Monoclonal);化学, 药物(Chemistry, Pharmaceutical);色谱法, 高压液相(Chromatography, High Pressure Liquid);免疫球蛋白G(Immunoglobulin G);光(Light);散射测浊法和比浊法(Nephelometry and Turbidimetry);蛋白质类(Proteins);温度(Temperature);超速离心法(Ultracentrifugation)
DOI
10.1002/jps.22034
PMID
20039394
发布时间
2019-12-10
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