Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development.
作者:
主题词
动物(Animals);碱性螺旋-环-螺旋转录因子类(Basic Helix-Loop-Helix Transcription Factors);印迹法, RNA(Blotting, Northern);细胞, 培养的(Cells, Cultured);胚胎, 哺乳动物(Embryo, Mammalian);胚胎, 非哺乳动物(Embryo, Nonmammalian);内分泌细胞(Endocrine Cells);内胚层(Endoderm);基因表达调控, 发育期(Gene Expression Regulation, Developmental);胃促生长素(Ghrelin);胰高血糖素(Glucagon);同源盒结构域蛋白质类(Homeodomain Proteins);免疫组织化学(Immunohistochemistry);原位杂交(In Situ Hybridization);胰岛(Islets of Langerhans);小鼠(Mice);神经组织蛋白质类(Nerve Tissue Proteins);成对盒转录因子类(Paired Box Transcription Factors);胰腺(Pancreas);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);生长抑素(Somatostatin);干细胞(Stem Cells);转录因子(Transcription Factors);翼螺旋转录因子类(Winged-Helix Transcription Factors);斑马鱼(Zebrafish);斑马鱼蛋白质类(Zebrafish Proteins)
DOI
10.1242/dev.041673
PMID
20040487
发布时间
2021-10-20
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