换一批
换一批Pharmacokinetics of humanized monoclonal anti-tumor necrosis factor-{alpha} antibody and its neonatal Fc receptor variants in mice and cynomolgus monkeys.
第一作者：
Rong,Deng
第一单位：
Department of Pharmacokinetics and Pharmacodynamics Sciences, Genentech Inc., South San Francisco, CA 94080, USA. deng.rong@gene.com
作者：
主题词
动物(Animals);动物, 新生(Animals, Newborn);抗体, 封闭(Antibodies, Blocking);抗体, 单克隆(Antibodies, Monoclonal);生物利用度(Biological Availability);人类(Humans);氢离子浓度(Hydrogen-Ion Concentration);注射, 静脉内(Injections, Intravenous);注射, 皮下(Injections, Subcutaneous);成束猴(Macaca fascicularis);小鼠(Mice);小鼠, SCID(Mice, SCID);受体, Fc(Receptors, Fc);种特异性(Species Specificity);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)
DOI
10.1124/dmd.109.031310
PMID
20071453
发布时间
2025-02-12
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