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Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease.

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第一作者： Minerva M,Carrasquillo

第一单位： Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, Florida, United States of America.

作者： Minerva M,Carrasquillo ^[1] ; Olivia,Belbin ; Fanggeng,Zou ; Mariet,Allen ; Nilufer,Ertekin-Taner ; Morad,Ansari ; Samantha L,Wilcox ; Mariah R,Kashino ; Li,Ma ; Linda H,Younkin ; Samuel G,Younkin ; Curtis S,Younkin ; Toros A,Dincman ; Melissa E,Howard ; Chanley C,Howell ; Chloe M,Stanton ; Christopher M,Watson ; Michael,Crump ; Veronique,Vitart ; Caroline,Hayward ; Nicholas D,Hastie ; Igor,Rudan ; Harry,Campbell ; Ozren,Polasek ; Kristelle,Brown ; Peter,Passmore ; David,Craig ; Bernadette,McGuinness ; Stephen,Todd ; Patrick G,Kehoe ; David M,Mann ; A David,Smith ; Helen,Beaumont ; Donald,Warden ; Clive,Holmes ; Reinhard,Heun ; Heike,Kölsch ; Noor,Kalsheker ; V Shane,Pankratz ; Dennis W,Dickson ; Neill R,Graff-Radford ; Ronald C,Petersen ; Alan F,Wright ; Steven G,Younkin ; Kevin,Morgan

作者单位： Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, Florida, United States of America. ^[1]

医学主题词阿尔茨海默病(Alzheimer Disease);淀粉样β肽类(Amyloid beta-Peptides);病例对照研究(Case-Control Studies);人类(Humans);胰岛素溶酶(Insulysin);RNA, 信使(RNA, Messenger)

DOI 10.1371/journal.pone.0008764

PMID 20098734

发布时间 2025-05-29

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